@A MySpondylitisTeam Member. Whichever one targets the specific cytokine causing your individual body's inflammation, if it is indeed caused by a cytokine. Look up what the one(s) being recommended to you target. The body can produce hundreds of different types of cytokines. Each biologic targets one. That is the problem with biologics. Drs do not routinely test patients for cytokines to determine which, if any, biologic is needed, even though a test for that actually does exist. To complicate matters, it's possible that the inflammatory cytokine changes and that is why a biologic might work for awhile, if at all, then stop working. Do your own research on this at National Institute of Health and European Medicines Agency. Dont fall into the "stop the patient's complaining and give them anything" trap.
Your best treatments are to determine the cause of your particular inflammation and work to stop that cause. Biologics are a very small part of the solution and often not any part of it at all. Research how your proposed biologic is manufactured, what it does. And pay very close attention to the side affects which, according to my personal experience and reading that of hundreds of others on this and other sites, will almost certainly occur. Are you willing to risk your kidneys and liver for maybe a little joint pain relief?
If biologics were as fantastic a wonder drug as commercials and doctors give hope for, do you think there would be thousands of sufferers on this site still looking for relief? Kindest regards and best of luck to you. Feel free to read posts about this and other topics from physical therapy to surgery and stem cells on my wall. Reach out anytime. 😌🙏

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