Extreme weakness can be a symptom of spondylitis-related fatigue, which is influenced by factors like inflammation, anemia, medication side effects, and poor sleep. Anemia, common in spondylitis, reduces oxygen delivery to tissues, worsening fatigue. Weakness may also stem from muscle strain or nerve involvement. Consult a Show Full Answer
Do Side Effects Of Methotrexate Injections Eventually Go Away? Had 4 Shots Once A Week So Far. Nauseated And Weak For 2-3 Days Afterwards.