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Real members of MySpondylitisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

My Doctor Wants To Put Me On Humira And Plaquenil, But I Have Concerns About Side Effects. I Would Like Opinions About Experiences Of These

A MySpondylitisTeam Member asked a question 💭
Howell, MI
January 13
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A MySpondylitisTeam Member

I recently took gabapentin at the 300 mg starter dose, it helped, I woke up one day and had huge big bruises,almost looked like …chemical burns, I had several and they hurt, then I became delirious Christmas Eve Morning and. Christmas night, (we are going to have Christmas at some point). My husband was afraid to call anyone for help for fear they would admit me to the hospital! & anyone would have thought these huge bruises that looked like burns may have came from him! , once I was headed for the stairs, surely would have fallen - just mentioning this again because it reminded me fear of side effects is not just being dramatic! The last one is still visible……I will want to know more about side effects from now on! Good thinking!

January 19
A MySpondylitisTeam Member

I have been taking lyrica for 2 years now. It has helped with nerves in legs, feet and now nerve pain in jaw. Only can take at night really makes your sleepy.

January 16
A MySpondylitisTeam Member

Having reach the limit to what over the counter medications can offer, I think I would welcome Humira and Plaquenil. It’s always a cost benefit analysis. My stomach has been destroyed by ibuprofen, various other arthritic medicines and steroids. I still take them because I do get some relief. I just would like to be a little more active.

January 13
A MySpondylitisTeam Member

Humira (Adalimumab) for Spondylitis

Administration:
- Initial Dose: Loading dose followed by maintenance.
- Frequency: Every other week.
- Method: Subcutaneous injection (pen or prefilled syringe).

Common Side Effects:
- Respiratory infections
- Headache
- Redness or irritation at injection sites
- Rash

Serious Side Show Full Answer

Humira (Adalimumab) for Spondylitis

Administration:
- Initial Dose: Loading dose followed by maintenance.
- Frequency: Every other week.
- Method: Subcutaneous injection (pen or prefilled syringe).

Common Side Effects:
- Respiratory infections
- Headache
- Redness or irritation at injection sites
- Rash

Serious Side Effects:
- Severe allergic reactions
- Potentially fatal infections
- Increased risk of certain cancers (e.g., lymphoma)

Additional Resources:
- For pregnancy and breastfeeding concerns, visit [MothertoBaby.org](https://www.mothertobaby.org).

For more details, visit the [Humira – AbbVie](https://www. humirapro.com/) website.

General Advice on Biologic Side Effects

Common Side Effects:
- Temporary soreness at the injection site
- Short-lived flu-like symptoms

Risks:
- Increased risk of infection due to immune system suppression

Management:
- Report any unexpected side effects to your doctor immediately.
- Discuss any difficulties in taking the medication with your healthcare provider to find suitable solutions.

For more information, you can watch the video on [Side Effects of Biologics](https://www.MySpondylitisTeam.com/resources/exp...).

Note:
Unfortunately, there is no information provided about Plaquenil in the knowledge base. If you have specific concerns, it is best to discuss them directly with your healthcare provider.

July 11
A MySpondylitisTeam Member

Unfortunately, medicine doesn’t want to discuss side effects. One of my major side effects is not being able to sleep. I take both Gabapentin and Lyrica.

January 20

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