Abrilada (Adalimumab-afzb) for Spondylitis

Overview
Abrilada is a prescription medication approved by the Food and Drug Administration (FDA) to reduce signs and symptoms of active ankylosing spondylitis in adults. Abrilada may be referred to by its drug name, Adalimumab-afzb.

Abrilada is a biosimilar of Humira. As defined by the FDA, a biosimilar is a biological product that is approved based on a showing that it is highly similar to an already-approved biological product.

Abrilada is an immunomodulator, or in other words, a drug that modulates the immune system. It is considered a biologic disease-modifying antirheumatic drug (DMARD). Abrilada is a genetically engineered antibody, or protein used by the immune system to identify and neutralize substances. Abrilada is believed to work by inhibiting tumor necrosis factor alpha (TNF-α), a chemical messenger involved in autoimmune attacks.

How do I take it?
Abrilada is administered as a subcutaneous injection every week or every other week.

Abrilada is available as single-use, prefilled pen or prefilled glass syringe.

Side effects
The FDA-approved label for Abrilada lists common side effects including headache, rash, infections, and injection site reactions.

Rare but serious side effects listed for Abrilada can include severe infections, heart failure, increased risk for certain types of cancer, lupus-like syndrome, severe allergic reactions, and the development of demyelinating conditions such as multiple sclerosis.

For answers to frequently asked questions about exposure to Adalimumab during pregnancy and breastfeeding, visit the experts at MothertoBaby.org.

For more details about this treatment, visit:

ABRILADA™ INJECTION (ADALIMUMAB-AFZB) - Pfizer
https://www.pfizer.com/products/product-detail/...